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VBI Vaccines Announces Acquisition of Epixis and Its Innovative eVLP Vaccine Platform

By September 15, 2011Archived Press Releases

VBI Vaccines (“VBI”), a biotechnology company dedicated to the innovative formulation, development and delivery of safe and effective vaccines, announced today that it has completed the acquisition of Epixis S.A., a French biotechnology company developing its “eVLP” platform technology for a new generation of Virus-Like Particle (VLP) vaccines. The acquisition is complementary to VBI’s suite of thermostable vaccine formulation technologies and enables VBI to develop its own VLP-based vaccines.

“This acquisition enables VBI to strategically build upon our pipeline of innovative vaccine delivery technologies and advance the development of an extremely promising VLP platform,” said Jeff Baxter, president and chief executive officer of VBI.

VBI and Epixis forged a VLP research collaboration focused on cytomegalovirus (CMV) in June 2010. That successful program made significant research advances in the past year that led to this acquisition and will now be VBI’s priority VLP vaccine candidate.

“There is an undeniable need for a safe and effective CMV vaccine,” said Baxter. “This intersection of scientific innovation and global patient demand is invigorating for all of us and we look forward to continuing our work with Epixis, now as a seamless part of the VBI team.”

Prior to initiating work on CMV, Epixis demonstrated successful proof of concept for its eVLP platform with a vaccine targeting Hepatitis C virus. These preclinical results were recently published in Science Translational Medicine. Given these promising findings, VBI is also developing its strategy to advance a Hepatitis C vaccine candidate.

“Our proof of concept and preclinical findings have been extremely promising in both CMV and Hepatitis C and we believe clearly demonstrate the value of the eVLP platform,” said Charlotte Dalba, Ph.D., M.B.A., former chief executive officer of Epixis and now a Senior Consultant with VBI.

Terms of the acquisition were not disclosed.

About VBI Vaccines

VBI Vaccines Inc. (“VBI”) is a biopharmaceutical company developing novel technologies that seek to expand vaccine protection in large underserved markets. VBI’s eVLP vaccine platform allows for the design of enveloped (“e”) virus-like particle (“VLP”) vaccines that closely mimic the target virus. VBI’s lead eVLP asset is a prophylactic Cytomegalovirus (“CMV”) vaccine; VBI has initiated work for GMP manufacturing of its CMV candidate for use in formal preclinical and Phase I trials. VBI’s LPV platform is a thermostable technology that enables the development of vaccines and biologics that can withstand storage or shipment at constantly fluctuating temperatures. VBI has completed proof of concept thermostability studies on a number of vaccine and biologic targets. VBI is headquartered in Cambridge, MA with research facilities in Ottawa, Canada.

VBI Company Contact

Jeff Baxter, President and CEO
Phone: (617) 830-3031 x125
Email: ir@vbivaccines.com

VBI Investor Contacts

Robert B. Prag, President
The Del Mar Consulting Group, Inc.
Phone: (858) 361-1786
Email: bprag@delmarconsulting.com

Scott Wilfong, President
Alex Partners, LLC
Phone: (425) 242-0891
Email: scott@alexpartnersllc.com

Forward-Looking Statement Disclosure

This press release contains certain “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including statements regarding the efficacy of potential products, the timelines for bringing such products to market, and the availability of funding sources for continued development of such products. Forward-looking statements are based on management’s estimates, assumptions, and projections, and are subject to uncertainties, many of which are beyond the control of VBI. Actual results may differ materially from those anticipated in any forward-looking statement. Factors that may cause such differences include the risks that potential products that appear promising to VBI cannot be shown to be efficacious or safe in subsequent preclinical or clinical trials, VBI will not obtain appropriate or necessary governmental approvals to market these or other potential products, VBI may not be able to obtain anticipated funding for its development projects or other needed funding, and VBI may not be able to secure or enforce adequate legal protection, including patent protection, for its products. All forward-looking statements included in this press release are made only as of the date of this press release, and VBI does not undertake any obligation to publicly update or correct any forward-looking statements to reflect events or circumstances that subsequently occur or of which we hereafter become aware.

More detailed information about VBI and risk factors that may affect the realization of forward-looking statements, including the forward-looking statements in this press release, is set forth in VBI’s filings with the Securities and Exchange Commission (the “Commission”). VBI urges investors and security holders to read those documents free of charge at the Commission’s Web site at http://www.sec.gov. Interested parties may also obtain those documents free of charge from VBI. Forward-looking statements speak only as to the date they are made, and except for any obligation under the U.S. federal securities laws, VBI undertakes no obligation to publicly update any forward-looking statement as a result of new information, future events or otherwise.